Low Dose Naltrexone (LDN) when I asked my GI about it he acted like I was speaking another language.  I explained that it was an alternative or non mainstream drug that was being used to treat Crohn's Disease, this was about a year ago.  Understand that my GI was a teacher, so he comes very qualified.  He not only blew me off but wouldn't even research it.  Now there are groups of sufferers who have banned together to find doctors who will prescribe the drug or alternatively find ways to get the drug from legal sources.   Many are compounding their own drug and finding relief from this.  It is a drug that was or is used to treat opioid addiction.  In very small doses it helps Crohn's Disease or so many people say.  If my liver was healthy enough to handle it, I would so give it a try.  Also, my understanding of it is that it also cannot be tolerated or taken with pain medications.  When you are desperately hurting it is hard to go off the pain medications to go on this new medication, however when my liver get's well enough I will.  Even if it means going to an alternative way to treat my pain, I'm sure you get my drift.  There was a Drug Trial done on this medication and it had pretty good success but I suppose because it is not a big money maker and probably are no kick backs being given it will probably never see the day of being used to treat symptoms of Crohn's Disease.